This book provides a comprehensive resource on the intrinsic and pathological aberrations of the complex process of elastic matrix assembly and/or variations thereof in different elastic tissue types, and on strategies to regenerate or restore lost elastin matrix, either in vitro or in vivo, including biomimetic elastin-like-peptides, gene therapy, drug delivery, tissue engineering, pharmacological approaches, elastin stabilization and preservation, stem cell therapy, allografts/xenografts, and synthetic/biological elastomers. The text details current approaches for elastin matrix regeneration and repair, identifying their various advantages and limitations.