Clinical and Molecular Heterogeneity of Osteogenesis Imperfecta (Colloquium Series on Genomic and Molecular Medicine)

Osteogenesis imperfecta (OI) is a disease encompassing a group of disorders mainly characterized by bone fragility and is the commonest form of heritable bone fragility. In this book, the clinical presentations with particular emphasis on rare phenotypes associated with OI are discussed together with molecular advances in diagnosis and treatment of OI.