§07§This book examines free radical-induced cellular damage in a variety of tissues and organs, bringing clinical insights to diseases where free radicals have been implicated. Discusses success and limitations of the use of antioxidants in clinical settings. Title is also available as part of a set: Systems Biology of Oxidative Stress (978-3-642-30019-6) §16§The focus of this collection of illustrated reviews is to discuss the systems biology of free radicals and anti-oxidants. Free radical induced cellular damage in a variety of tissues and organs is reviewed, with detailed discussion of molecular and cellular mechanisms. The collection is aimed at those new to the field, as well as clinicians and scientists with long standing interests in free radical biology. A feature of this collection is that the material also brings insights into various diseases where free radicals are thought to play a role. There is extensive discussion of the success and limitations of the use of antioxidants in several clinical settings. § §04§§SECTIONS: General topics.- Embryology and Neonatal.- Hematology/Tissue repair.- Dermatology.- Genitourinary.- Cancer.- Pulmonary.- Musculoskeletal.- Gastrointestinal.- Immunology and Inflammation.- Endocrinology.- Plant-derived Anti-Oxidants.- Exercise, Ear, Nose and Throat.- Clinical Aspects. § §02§§Ismail (Issy) Laher, Ph.D., is a Professor at the Department of Pharmacology and Therapeutics at the Faculty of Medicine of the University of British Columbia in Vancouver,Canada. He is also a Visiting Professor at the Department of Pharmacology at the University of Vermont, USA. Trained at the University of London in pharmacology, he then continued with additional training in cardiovascular pharmacology at UBC and UVM, with a focus on the regulation of resistance artery regulation in health and disease. §
