Transgenic Mutagenicity Assays (Environmental Health Criteria)

A product of the International Programme on Chemical Safety (a joint venture of the United Nations Environment Programme, the International Labor Organization, and the World Health Organization), this monograph contains an introduction to the field of transgenic mutagenicity assays. It is primarily a review of the literature that provides an overview of genotoxicity testing and transgenic animal mutagenicity systems, compares different models with conventional test systems, and describes applications in mechanistic studies. It also evaluates the value of transgenic animal mutagenicity assays for toxicology testing and mechanistic research based on the review of the literature. Annotation 2007 Book News, Inc., Portland, OR (booknews.com)