Medicinal plants supply the ever-growing needs of humankind for natural chemicals, such as pharmaceuticals, nutraceuticals, agrochemicals, and chemical additives. These plants contain bioactive secondary metabolites, which possess antimalarial, anthelminthic, anti-inflammatory, analgesic, antimicrobial, antiarthritic, antioxidant, antidiabetic, antihypertensive, anticancer, antifungal, antispasmodic, cardioprotective, antithyroid, and antihistaminic properties. Secondary metabolites play a major role in the adaptation of plants to the changing environment and stress condition as they are affected by both biotic and abiotic stress. Humans rely on medicinal plants for various needs since ancient time, and their population still seems enough for fulfilling our demands. However, in the foreseeable future, we will be forced to think about the accessibility of resources for future generations. For these reasons, we must look for alternative sustainable options of resources which can protect these immensely important medicinal plants from various stresses induced by challenging environment. Evolving eco-friendly methodologies and mechanisms to improve these plants'' responses to unfavorable environmental circumstances is important in creating significant tools for better understanding of plant adaptations to various abiotic stresses and sustaining the supply of pharmaceuticals as global climate change intensifies.
One of the great challenges in the near future will be the sustainable production of medicinal plants under increasing adverse effects of climate change. A combination of adverse demographic factors and climatological perturbations is expected to impact food and pharmaceutical production globally. Despite the induction of several tolerance mechanisms, medicinal plants often fail to survive under environmental extremes. To ensure their sustainable production under adverse conditions, multidisciplinary approaches are needed, and useful leads are likely to
