This book extends the first volume with contributions that advance the state of the art and demonstrate their impact in real-world applications. In a few years, the convergence of artificial intelligence (AI) and quantum computing has moved from speculation to concrete prototypes and tools. Key Highlights• Health and Precision Medicine: Deep learning and hybrid quantum–classical models support osteoporosis screening from dental radiographs, Alzheimer’s staging with 3D MRI, EEG-based cognitive-state assessment, and HIV/TB biomarker classification, strengthening prevention, diagnosis, and personalized treatment. • Education, Human–AI Interaction and Fairness: An automatic reviewer of handwritten flowcharts scales feedback in programming courses, while a benchmarking study on speaker ID and gender recognition analyzes bias; quantum granular computing provides a Hilbert-space framework for advanced teaching and research. • Sustainable Production, Cities, and Environment: Vision systems for welding defects, cucumber disease detection, and analogue water-meter digitization improve manufacturing quality, reduce food waste, and enable transparent water management, alongside work on electric fleets, mobile robots, and sea turtle monitoring. • Data-Centric and Trustworthy AI for the Digital Economy: GAN-based synthetic tabular data, decision-support for cryptocurrency markets, and benchmarks for intrusion detection and malware classification offer tools for scarce or volatile data, with emphasis on robustness, interpretability, and reproducible evaluation. • Quantum Algorithms, Hardware and Software Infrastructure: Chapters address quantum optimization (QAOA, adiabatic 3-SAT), quantum error correction and superconducting devices, plus experimental QKD, while a C-to-QIR compiler and quantum granules framework provide software and conceptual support for hybrid systems. •Optimization and Intelligent Systems: Fuzzy fractal search and fuzzy dragonfly metaheuristics optimize neural
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