In 12 chapters, genetics, molecular biomedicine, and other researchers from around the world detail advances in basic applied RNA interference (RNAi) medical research and applications in RNAi-based therapies. They discuss biogenesis and applications of microRNA; non-canonical microRNA biogenesis and function; non-coding RNAs and the epigenetic control of gene expression; the clinical translation of microRNA technologies for somatic cell reprogramming; systems biology tools for understanding the role of host microRNAs in infection, particularly in HIV; synthetic microRNA blocking agents; using microRNAs to regulate transgene expression, for gene silencing, and using RNAi for the treatment of viral infections; the role of microRNAs in cancers associated with human tumor viruses; microRNAs as cancer biomarkers; and microRNA deregulation in trinucleotide repeat expansion disorders. Distributed in the US by ISBS. Annotation 2014 Ringgold, Inc., Portland, OR (protoview.com)
