Natural Products in Chemical Biology

A timely and authoritative look at the chemistry of natural products Based on the acclaimed Wiley Encyclopedia of Chemical Biology, this book focuses on natural products and explores their impact on drug discovery and design. With emphasis on the gamut of biological diversity and activities of natural products, the book examines the unique features of these molecules, highlights influences from genetics and biochemistry, and points to promising future trends. Divided into three parts, Natural Products in Chemical Biology first introduces sources of natural products, then goes on to present the biosynthesis of main classes of natural products and their uses in medicine. The book presents fourteen self- contained, peer-reviewed articles carefully selected from the Wiley Encyclopedia of Chemical Biology and new material. Clear, authoritative coverage includes: A discussion of the chemical diversity of plant, marine, and microbial natural products Biosynthesis of nonribosomal peptides, plant terpenoids, polyketides, alkaloids, cofactors, and antibiotics Use of natural products and natural product models in the pharmaceutical industry Natural Products in Chemical Biology is an excellent introduction to the ongoing research in the chemistry of natural products for researchers in diverse fields, from organic and medicinal chemistry to molecular biology and the pharmaceutical industry.