Peripheral Arterial Disease : Pathophysiology and Therapeutics (Colloquium Series on Integrated Systems Physiology: From Molecule to Function)

Peripheral arterial disease (PAD) is a cardiovascular disorder of the peripheral vasculature due to progressive atherosclerotic stenosis of conduit arteries restricting blood flow to tissues. PAD is typically a disease of older individuals. This title discusses PAD signs and symptoms, pathophysiological mechanisms, current management, and future disease targets and possible therapeutic treatments.