Mouse Models of Cancer : A Laboratory Manual

"99% of mouse protein-coding genes have an equivalent homolog in the human genome, despite the striking differences in appearance between mouse and man. This remarkable genetic similarity, together with our ability to finely engineer the murine genome, has made the mouse the ideal animal in which to model and analyze human biology and disease. This book envisages the next generation of mouse models, and it also addresses the strategic use of mice in the fight against cancer"--