§16§§This book provides a comprehensive account on individually rare, but collectively frequent diseases of the liver. In the first part, conditions such as hepatic vascular malformations, ischemic cholangiopathy, hepatic artery occlusion, sinusoidal conditions and Budd-Chiari syndrome are discussed among others. The second part examines the causes of vascular liver disease namely, coagulation disorders, neoplasm disorders, non-malignant blood disorders, systemic diseases and toxins, among others. § §The unique expertise of the authors, who are all members of the Vascular Liver Disease Disorders Group, an independent network of researchers with a common interest in Vascular Liver Diseases, are merged for an optimal pragmatic and individualized approach.§ This book is of interest to a broad range of experts, such as hepatologists, internists, radiologists and angiologists.§§§§ §04§§Section 1-Vascular Disorders of the Liver and Their Management.- Role of liver biopsy in the study of vascular disorders of the Liver.- Role of imaging in the study of vascular disorders of the Liver.- Hepatic artery occlusion and ischemic cholangiopathy.- Other disorders of hepatic arteries (aneurysms, arterioportal fistulas).- Hepatic vascular malformations in hereditary hemorrhagic telangiectasia.- Congenital portosystemic shunts - Abernethy malformation.- Budd-Chiari syndrome - Hepatic venous outflow tract obstruction.- Extrahepatic portal vein obstruction - Portal vein thrombosis and portal cavernoma in the absence of cirrhosis.- Portal vein thrombosis in patients with cirrhosis.- Portal-sinusoidal disease.- Sinusoidal obstruction syndrome/Hepatic veno-occlusive disease.- Sinusoidal dilatation/Peliosis.- Hypoxic hepatitis.- Congestive cardiac hepatopathy.- Regenerative nodules and liver tumors in vascular liver diseases.- Pregnancies and contraception in patients with va §04§scular liver diseases.- Antithrombotic therapy and liver disease (including thrombolysis, DOACS).- Section 2- Causes for Vascular Disorders of the Liver.- Coagulation disorders and the liver (including DIC and related conditions such as HELLP/preeclampsia).- Hematologic and non-hematologic neoplasm disorders affecting liver vessels (microscopic or gross invasion, including alveolar echinococcosis).- Non-malignant blood disorders affecting liver vessels (sickle cell disease, hemophagocytic syndrome, primary immune deficiency syndromes, HIV infection, etc.).- Systemic diseases affecting liver vessels (periarteritis nodosa, Behcet's disease, systemic lupus, systemic sclerosis, rheumatoid arthritis, sarcoidosis, diabetes).- Drugs and toxins affecting liver vessels.- The Fontan circulation and the liver.§ §02§Dominique-Charles VALLA, is Professor of Hepatology, and Head of the Département Hospitalo-Universitaire UNITY. He is affiliated to the Service d'hépatologie, Hôpital Beaujon, Clichy-la-Garenne; the Centre national de référence, Maladies Rares, Maladies Vasculaires du Foie (CRMVF) ; the Université Paris Diderot, Paris; and the CRI, Inserm U1149, Paris. He was the co-founder and coordinator of the European Network for Vascular Disorders of the Liver (EN-Vie), 2000-2005; the founder and head of CRMVF, 2006-2016; and the Head of the Service d'Hépatologie, Hôpital Beaujon, 1999-2013. He served as Associate Editor for Gastroentérologie Clinique et Biologique, and Journal of Hepatology; as Editor-in-Chief (Hepatology) for Hepato-Gastro. He is a member of the French Association for the Study of the Liver - AFEF; of the French Society of Gastroenterology - SNFGE (where is served as governing board member, 2007-2016, and President in 2015); of the European Association for the Study of the §02§ Liver - EASL (where he served as governing board member 2009-2012, policy counsellor 2008-2012, and member of UEG public affair committee 2009-2012); and the American Association for the Study of the Liver - AASLD. He has authored articles, chapters of books and delivered conferences on vascular disorders of the liver, the liver in systemic diseases, portal hypertension and the complications of cirrhosis. He has authored 425 publications in peer-review journals
