§16§Hantaviruses are found world-wide and are associated with two severe disease syndromes, hemorrhagic fever and hantavirus pulmonary syndrome. The recent studies in this volume provide a basis for understanding the high human pathogenicity of theses viruses and their continued maintenance and transmission within rodent populations. §04§List of Contents.- Hantaviruses: History and Overview.- Replication of Hantaviruses.- Hantavirus Maturation.- Virus Evolution and Genetic Diversity of Hantaviruses and Their Rodent Hosts.- Modeling Hantavirus Maintenance and Transmission in Rodent Communities.- Cellular Receptors and Hantavirus Pathogenesis.- Clinical Manifestations of New World Hantaviruses.- Clinical Characteristics of Hantavirus Infections on the Eurasian Continent.- Human Immune Response, Host Genetics, and Severity of Disease.- Vaccines Against Hantaviruses. §02§The recent studies reviewed in this volume impart considerable insight into hantavirus replication, pathogenesis and evolution, and provide a basis for understanding the high human pathogenicity of these viruses and their continued maintenance and transmission within rodent populations. c