This edition is a record of James Watson’s historic visit to Greece in 2011 and 2016 at the Postgraduate Program «Medical Chemistry» conferences of the University of Patras. At these conferences, with James Watson as the honored person, the opportunity was given for the Greek University Community to get to know the great research-er up close. The discovery of the structure and function of the double-stranded DNA of Watson and Crick was one of the most important achieve-ments of the human mind and a huge step of man in his course through the centuries. It is considered the most important discovery after the formulation of the theory of evolution by Charles Darwin. The discovery of the function of DNA confirmed the theory of evolution and is now the core and reference point of all sciences that evolve over time, drawing on the wisdom of deciphering the secret of the molecule of life, in the service of all sciences. Knowledge of the structure of the DNA molecule and the genome that carries the genetic information has opened new horizons in the fields of molecular biology and gives new perspectives to the science of biology and medicine for new therapies. For their momentous discovery, Watson and Crick were awarded the Nobel Prize in Medicine and Physiology in 1962 and now belong to the pantheon of pioneers of the human intellect alongside the leading figures whose work has influenced human thought. Their discovery led to the revision of the fundamental rules of all the sciences and the perception with which man saw himself and the world. Their discovery was the beginning of a new world that saw and explained life and its mysteries in the light of scientific truth. Watson and Crick will be referred to the next generations alongside the leading figures of human thought. The discovery and deciphering of DNA was the great leap of medicine after Hippocrates and Watson and Crick’s Eureka –we discovered the secret of life– was the most important statement ever heard after Arc